Enokido T, Horie M, Yoshino S, Suzuki HI, Matsuki R, Brunnström H, Micke P, Nagase T, Saito A, Miyashita N.
Distinct microRNA Signature and Suppression of ZFP36L1 Define ASCL1-Positive Lung Adenocarcinoma.
Mol Cancer Res. 2024 Jan 2;22(1):29-40.
PMID: 37801008

Isago H, Watanabe K, Satoh Y, Kurano M.
Correlation between variant call accuracy and quality parameters in comprehensive cancer genomic profiling tests.
Pract Lab Med. 2024;39:e00369.
PMID: 38404524

Isago H, Uranbileg B, Mitani A, Kurano M.
Understanding the modulations of glycero-lysophospholipids in an elastase-induced murine emphysema model.
Biochem Biophys Res Commun. 2024 Jan 29:694:149419.
PMID: 38145597

Nishiyama A, Shimizu M, Narita T, Kodera N, Ozeki Y, Yokoyama A, Mayanagi K, Yamaguchi T, Hakamata M, Shaban AK,
Tateishi Y, Ito K, Matsumoto S.
Dynamic action of an intrinsically disordered protein in DNA compaction that induces mycobacterial dormancy.
Nucleic Acids Res. 2024 Jan 25;52(2):816-830.
PMID: 38048321

Watanabe K, Kohsaka S, Tatsuno K, Ushiku A, Isago H, Kage H, Ushiku T, Aburatani H, Mano H, Oda K.
Analysis of quality metrics in comprehensive cancer genomic profiling using a dual DNA-RNA panel.
Pract Lab Med. 2024;39:e00368.
PMID: 38404525

Fukuda K, Matsuzaki H, Hiraishi Y, Miyashita N, Ishii T, Yuki M, Isago H, Tamiya H, Mitani A, Saito A, Jo T, Nagase T.
Anti-Inflammatory Effects of Japanese Herbal Medicine Hochuekkito in a Mouse Model of Acute Exacerbation of Chronic Obstructive Pulmonary Disease.
Pharmacology. 2024;109(2):121-126.
PMID: 38346407

Nakagawa S, Ono N, Hakamata Y, Ishii T, Saito A, Yanagimoto S, Kanaya S.
Quantitative evaluation model of variable diagnosis for chest X-ray images using deep learning.
PLOS Digit Health. 2024 Mar 15;3(3):e0000460.
  PMID: 38489375

Jang J, Zhou M, Makita K, Sun R, Hajjar M, Fonseca G, Lauzon A, Martin J.
Induction of a memory-like CD4+ T-cell phenotype by airway smooth muscle cells.
Eur J Immunol. 2024 Apr;54(4):e2249800.
PMID: 38334162

Matsumoto Y, Kage H, Morota M, Zokumasu K, Ando T, Maemura K, Watanabe K, Kawakami M, Hinata M, Ushiku T,
Nakajima J, Nagase T.
Integrin alpha 2 is associated with tumor progression and postoperative recurrence in non-small cell lung cancer.
Jpn J Clin Oncol. 2023 Jan 6;53(1): 63-73.
PMID: 36151049

Nakagawa N, Yamamoto S, Hanai A, Oiwa A, Arao H.
Exercise intervention for the management of chemotherapy-induced peripheral neuropathy: a systematic review and network meta-analysis.
Front Neurol. 2024 Jan 30:15:1346099.
PMID: 38352137

Mizuno S, Ikegami M, Koyama T, Sunami K, Ogata D, Kage H, Yanagaki M, Ikeuchi H, Ueno T, Tanikawa M, Oda K,
Osuga Y, Mano H, Kohsaka S.
High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.
Mol Cancer Ther. 2023;22:227-239
PMID: 36442478

Kimura Y, Jo T, Inoue N, Suzukawa M, Tanaka G, Kage H, Kumazawa R, Matsui H, Fushimi K, Yasunaga H, Matsui H.
Association Between Systemic Corticosteroid Use and Mortality in Patients with Epiglottitis.
Laryngoscope. 2023;133:344-349.
PMID: 35305022

Kage H, Shinozaki-Ushiku A, Ishigaki K, Sato Y, Tanabe M, Tanaka S, Tanikawa M, Watanabe K, Kato S, Akagi K, Uchino K, Mitani K, Takahashi S, Miura Y, Ikeda S, Kojima Y, Watanabe K, Mochizuki H, Yamaguchi H, Kawazoe Y, Kashiwabara K, Kohsaka S, Tatsuno K, Ushiku T, Ohe K, Yatomi Y, Seto Y, Aburatani H, Mano H, Miyagawa K, Oda K.
Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.
Cancer Sci. 2023 Apr;114:1710-1717
PMID: 36601953

Awano N, Urushiyama H, Yamana H, Yokoyama A, Ando T, Izumo T, Inomata M, Ito Y, Jo T.
Validity of diagnoses of respiratory diseases recorded in a Japanese administrative database.
Respir Investig. 2023 May;61(3):314-320.
PMID: 36868080

Horie M, Tanaka H, Suzuki M, Sato Y, Takata S, Takai E, Miyashita N, Saito A, Nakatani Y, Yachida S.
An integrative epigenomic approach identifies ELF3 as an oncogenic regulator in ASCL1-positive neuroendocrine carcinoma.
Cancer Sci. 2023 Jun;114(6):2596-2608.
PMID: 36840413

Mikami Y, Grubb BR, Rogers TD, Dang H, Asakura T, Kota P, Gilmore RC, Okuda K, Morton LC, Sun L, Chen G, Wykoff JA,
Ehre C, Vilar J, Heusden C, Alessandra LB, Gentzsch M, Button B, Stutts MJ, Randell SH, O'Neal WK, Boucher RC.
Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.
Sci Transl Med. 2023 Jun;15(699):eabo7728.
PMID: 37285404

Kage H, Oda K, Muto M, Tsuchihara K, Okita N, Okuma Y, Kikuchi J, Shirota H, Hayashi H, Kokuryo T, Sakai D, Hirasawa A,
Kubo M, Kenmotsu H, Akiyama N, Shinozaki-Ushiku A, Tanabe M, Ushiku T, Miyagawa K, Seto Y.
Human resources for administrative work to carry out a comprehensive genomic profiling test in Japan.
Cancer Sci. 2023;114:3041-3049
PMID: 37165760

Matsubara J, Mukai K, Kondo T, Yoshioka M, Kage H, Oda K, Kudo R, Ikeda S, Ebi H, Muro K, Hayashi R, Tokudome N,
Yamamoto N, Muto M.
First-Line Genomic Profiling in Previously Untreated Advanced Solid Tumors for Identification of Targeted Therapy Opportunities.
JAMA Netw Open. 2023;6:e2323336
PMID: 37459099

Jo T, Shigemi D, Konishi T, Yamana H, Michihata N, Kumazawa R, Yokoyama A, Urushiyama H, Matsui H, Fushimi K, Nagase T, Yasunaga H.
Antiemetic Effect of Rikkunshito, a Japanese Kampo Herbal Medicine, on Cisplatin-induced Nausea and Vomiting: A Nationwide Database Study in Japan.
Intern Med. 2024 Apr 1;63(7):919-927.
PMID: 37495535

Fujita K, Arai R, Shoji S, Saito R, Nomura M, Hotta T, Asahina H, Kawakami M, Nakachi I, Hasegawa Y, Okafuji K,
Suzuki A, Miyanaga A, Sunaga N, Nagashima H, Ikeda N, Watanabe S, Nagai Y, Furuta M, Kage H, Arai D, Fukuhara T,
Nakayama M, Morita S, Kobayashi K, Hagiwara K.
Detection of multiple druggable mutations of lung cancer from cytology specimens by MINtS: An advanced medicine A trial.
Cancer Sci. 2023;114:3342-3351
PMID: 37139543

Kobayashi K, Saito Y, Kage H, Fukuoka O, Yamamura K, Mukai T, Oda K, Yamasoba T.
CDK12 alterations and ARID1A mutations are predictors of poor prognosis and therapeutic targets in high-grade salivary gland carcinoma: analysis of the National Genomic Profiling Database.
Jpn J Clin Oncol. 2023;53(9):798-807.
PMID: 37357968

Awano N, Jo T, Izumo T, Inomata M, Ito Y, Hashimoto Y, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H.
Hospital volume and outcomes following bronchoscopy in patients with interstitial lung disease: A retrospective observational study using a national inpatient database in Japan.
Respir Investig. 2023 Nov;61(6):720-728.
PMID: 37714090

Tamiya H, Mitani A, Abe M, Nagase T.
Putative Bidirectionality of Chronic Obstructive Pulmonary Disease and Periodontal Disease: A Review of the Literature.
J Clin Med. 2023;12(18):5935
PMID: 37762876

Yoshida Y, Nishiyama A, Suameitria Dewi DNS, Yamazaki T, Yokoyama A, Kobayashi D, Kondo H, Ozeki Y, Matsumoto S.
Limited proteolysis of mycobacterial DNA-binding protein 1 with an extended, lysine-rich, intrinsically disordered region to unveil posttranslational modifications.
Biochem Biophys Res Commun. 2023 Nov 12;681:111-119.
PMID: 37774568

Fujii K, Fukuda K, Kawakami M, Mitani A, Tanaka G, Kage H.
Lung Adenocarcinoma Size Decrease after SARS-CoV-2 Vaccination during Long-Term Pembrolizumab Treatment: A Case Report.
Case Rep Oncol. 2023;16:907-911
PMID: 37900823

Nakai T, Watanabe T, Kaimi Y, Shiomi K, Ando K, Miyamoto A, Ogawa K, Matsumoto Y, Sawa K, Sato K, Asai K,
Matsumoto Y, Mikami Y, Ohsawa M, Kawaguchi T.
Diagnostic Utility and Safety of Non-Intubated Cryobiopsy Technique Using a Novel Ultrathin Cryoprobe in Addition to Conventional Biopsy Techniques for Peripheral Pulmonary Lesions.
Respiration. 2023;102(7):503-514.
PMID: 37379810

Kato H, Kimura S, Taguchi M, Sunouchi T, Hoshino Y, Hidaka N, Edvige Foligno N, Koga M, Manaka K, Tamiya H,
Kawakami M, Kage H, Yasunaga Y, Nangaku M, Makita N, Ito N.
FGF23-related hypophosphatemia in a patient with small cell lung cancer: a case report and literature review.
Endocr J. 2023;70:1005-1013
PMID: 37468265

Awano N, Jo T, Izumo T, Inomata M, Ito Y, Morita K, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H.
Polymyxin B-immobilised fibre column treatment for acute exacerbation of idiopathic pulmonary fibrosis patients with mechanical ventilation: a nationwide observational study.
J Intensive Care. 2023 Oct 11;11(1):45.
PMID: 37821999

Tamiya H, Abe M, Nagase T, Mitani A.
The Link between Periodontal Disease and Asthma: How Do These Two Diseases Affect Each Other?
J Clin Med. 2023;12(21):6747
PMID: 37959214

Kobayashi H, Zhang L, Okajima K, Ishibashi Y, Hirai T, Tsuda Y, Ikegami M, Kage H, Shinozaki-Ushiku A, Oda K, Tanaka S.
BRAF mutations and concurrent alterations in patients with soft tissue sarcoma.
Genes Chromosomes Cancer. 2023;62:648-654
PMID: 37293958

Kobayashi K, Saito Y, Kamogashira T, Kage H, Fukuoka O, Yamamura K, Mukai T, Oda K, Yamasoba T.
Survival analysis of high-grade salivary gland carcinoma adjusted for length bias due to delay in comprehensive genomic profiling.
Jpn J Clin Oncol. 2023;53:1092-1093
PMID: 37781750

Yokoyama A, Jo T, Sakamoto Y, Urushiyama H, Tamiya H, Tanaka G, Kumazawa R, Matsui H, Fushimi K, Yasunaga H, Nagase T.
Effectiveness and safety of the co-administration of Yokukan-San (Japanese herbal medicine) with antipsychotics in hospitalized older patients with pneumonia.
Geriatr Gerontol Int. 2023 Nov;23(11):849-854.
PMID: 37804182

Konkimalla A, Konishi S, Macadlo L, Kobayashi Y, Farino ZJ, Miyashita N, El Haddad L, Morowitz J, Barkauskas CE,
Agarwal P, Souma T, ElMallah MK, Tata A, Tata PR.
Transitional cell states sculpt tissue topology during lung regeneration.
Cell Stem Cell. 2023 Nov 2;30(11):1486-1502.e9.
PMID: 37922879

Ohara K, Miyawaki S, Nakatomi H, Okano A, Teranishi Y, Shinya Y, Ishigami D, Hongo H, Takayanagi S, Tanaka S,
Shinozaki-Ushiku A, Kohsaka S, Kage H, Oda K, Miyagawa K, Aburatani H, Mano H, Tatsuno K, Saito N.
Case report and literature review: exploration of molecular therapeutic targets in recurrent malignant meningioma through comprehensive genetic analysis with Todai OncoPanel.
Front Neurol. 2023;14:1270046
PMID: 38073632

Tamiya H, Mitani A, Abe T, Nagase Y, Suzuki H, Jo T, Tanaka G, Nagase T.
Association between Inhalation Instruction Method in Community Pharmacies and Inhaler Device Handling Error in Patients with Obstructive Lung Disease: An Evaluation of the Impact of Practical Demonstration by Pharmacists.
Biol Pharm Bull. 2022;45(12):1764
PMID: 36450529

Saito Y, Kage H, Kobayashi K, Yoshida M, Fukuoka O, Yamamura K, Mukai T, Oda K, Yamasoba.
TERT promoter mutation positive oral cavity carcinomas, a clinically and genetically distinct subgroup of head and neck squamous cell carcinomas.
Head Neck. 2023;45:3107-3118
PMID: 37815002

Xi Q, Kage H, Ogawa M, Matsunaga A, Nishijima A, Sone K, Kawana K, Oda K.
Genomic Landscape of Endometrial, Ovarian, and Cervical Cancers in Japan from the Database in the Center for Cancer Genomics and Advanced Therapeutics.
Cancers (Basel). 2023;16:136
PMID: 38201563

Ando T, Kage H, Shinozaki-Ushiku A, Tatsuno K, Tsutsumi S, Nagayama K, Nakajima J, Kohsaka S, Miyagawa K,
Aburatani H, Mano H, Nagase T.
Composite Clonal Analysis Reveals Transition of NSCLC Subtypes Through Accumulation of Gene Mutations: A Case Report.
JTO Clin Res Rep. 2022 Jan 10;3(2):100277.
PMID: 35199052

Oki R, Hirakawa Y, Oda Y, Nakamura M, Honda K, Abe H, Domoto Y, Miyashita N, Nagase T, Nangaku M.
Renal-limited ANCA-associated vasculitis during erlotinib treatment for lung carcinoma.
CEN Case Rep. 2022; 11: 67-72.
PMID: 34309804

Murata M, Nakagawa N, Kawasaki T, Yasuo S, Yoshida T, Ando K, Okamori S, Okada Y.
Adverse events during intrahospital transport of critically ill patients: A systematic review and meta-analysis.
Am J Emerg Med. 2022 Feb;52:13-19.
PMID: 34861515

Mitani A, Hamada K, Yoshikawa N, Morita Y, Horie T, Inoue Y, Saito M, Ishii T, Sunohara M, Takahashi R, Emoto N,
Nishimoto N, Murano Y, Okazaki S, Tateishi S, Yao A, Shimura T, Kurano M, Yatomi Y, Yanagimoto S.
Epidemiological study using igm and igg antibody titers against sars-cov-2 in the university of tokyo, japan (ut-cats).
J Infect Chemother. 2021;27:1342-1349.
PMID: 34887175

Amano Y, Kage H, Tanaka G, Sato Y, Tanaka M, Nagase T.
Multiple Brain Metastases in a Patient with ROS1 Fusion-Positive Lung Adenocarcinoma as a Disease Flare due to Crizotinib Cessation Caused by Disseminated Aseptic Inflammation from Crizotinib-Associated Renal Cysts: A Case Report.
Case Rep Oncol. 2022;15:338-344.
PMID: 35529295

Kawasaki T, Nakagawa N, Murata M, Yasuo S, Yoshida T, Ando K, Okamori S, Okada Y.
Diagnostic accuracy of urinary antigen tests for legionellosis: A systematic review and meta-analysis.
Respir Investig. 2022 Mar;60(2):205-214.
PMID: 34972680

Awano N, Jo T, Izumo T, Inomata M, Morita K, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H.
Recombinant human soluble thrombomodulin for acute exacerbation of idiopathic pulmonary fibrosis: a nationwide observational study.
J Intensive Care. 2022 Mar 9;10(1):14.
PMID: 35264250

Miyamoto S, Yamazaki T, Shimizu K, Matsubara T, Kage H, Watanabe K, Kobo H, Matsuyama Y, Rodin G, Yoshiuchi K.
Brief, manualised and semistructured individual psychotherapy programme for patients with advanced cancer in Japan: study protocol for Managing Cancer and Living Meaningfully (CALM) phase 2 trial.
BMJ Open. 2022;12:e056136
PMID: 35277407

Tian D, Shiiya H, Takahashi M, Terasaki Y, Urushiyama H, Shinozaki-Ushiku A, Yan HJ, Sato M, Nakajima J.
Noninvasive monitoring of allograft rejection in a rat lung transplant model: Application of machine learning-based 18F-fluorodeoxyglucose positron emission tomography radiomics.
J Heart Lung Transplant. 2022 Jun;41(6):722-731.
PMID: 35430149

Kato T, Radicioni G, Papanikolas MJ, Stoychev GV, Markovetz MR, Aoki K, Porterfield M, Okuda K, Barbosa Cardenas SM,
Gilmore RC, Morrison CB, Ehre C, Burns KA, White KK, Brennan TA, Goodell HP, Thacker H, Loznev HT, Forsberg LJ,
Nagase T, Rubinstein M, Randell SH, Tiemeyer M, Hill DB, Kesimer M, O'Neal WK, Ballard ST, Freeman R, Button B,
Boucher RC.
Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis.
Sci Adv. 2022;8:eabm9718.
PMID: 35363522

Abe M, Mitani A, Zong L, Zhang CD, Hoshi K, Yanagimoto S.
High frequency and long duration of toothbrushing can potentially reduce the risk of common systemic diseases in late adolescence.
Spec Care Dentist. 2022 May; 42(3): 317-318.
PMID: 34687071

Roszik J, Lee JJ, Wu YH, Liu X, Kawakami M, Kurie JM, Belouali A, Boca SM, Gupta S, Beckman RA, Madhavan S, Dmitrovsky E.
Real-World Studies Link Nonsteroidal Anti-inflammatory Drug Use to Improved Overall Lung Cancer Survival.
Cancer Res Commun. 2022 Jul;2(7):590-601.
PMID: 35832288

Tanosaki T, Mikami Y, Shindou H, Suzuki T, Hashidate-Yoshida T, Hosoki K, Kagawa S, Miyata J, Kabata H, Masaki K, Hamamoto R, Kage H, Miyashita N, Makita K, Matsuzaki H, Suzuki Y, Mitani A, Nagase T, Shimizu T, Fukunaga K.
Lysophosphatidylcholine Acyltransferase 1 Deficiency Promotes Pulmonary Emphysema via Apoptosis of Alveolar Epithelial Cells.
Inflammation. 2022;45:1765-1779
PMID: 35338433

Nakagawa N, Kawakami M.
Choosing the optimal immunotherapeutic strategies for non-small cell lung cancer based on clinical factors.
Front Oncol. 2022 Aug 12;12:952393.
PMID: 36033471

Kage H, Kohsaka S, Tatsuno K, Ueno T, Ikegami M, Zokumasu K, Shinozaki-Ushiku A, Nagai S, Aburatani H, Mano H,
Oda K.
Tumor mutational burden measurement using comprehensive genomic profiling assay.
Jpn J Clin Oncol. 2022;52:925-929.
PMID: 35482395

Urushiyama H, Jo T, Hasegawa W, Yokoyama A, Ando T, Sakamoto Y, Kumazawa R, Uda K, Michihata N, Awano N,
Hiroki M, Fushimi K, Yasunaga H, Nagase T.
Effect of nintedanib on acute exacerbations of fibrosing interstitial lung diseases: a national database study in Japan.
ERJ Open Res. 2022 Nov 28;8(4):00209-2022.
PMID: 36451844

Miyakawa K, Miyashita N, Horie M, Terasaki Y, Tanaka H, Urushiyama H, Fukuda K, Okabe Y, Ishii T, Kuwahara N,
Suzuki HI, Nagase T, Saito A.
ASCL1 regulates super-enhancerassociated miRNAs to define molecular subtypes of small cell lung cancer.
Cancer Sci. 2022; 113(11): 3932-46.
PMID: 35789143

Imai M, Nakamura Y, Sunami K, Kage H, Komine K, Koyama T, Amano T, Ennishi D, Kanai M, Kenmotsu H, Maeda T,
Morita S, Sakai D, Bando H, Makiyama A, Suzuki T, Hirata M, Kohsaka S, Tsuchihara K, Naito Y, Yoshino T.
Expert panel consensus recommendations on the use of circulating tumor DNA assays for patients with advanced solid tumors.
Cancer Sci. 2022;113:3646-3656.
PMID: 35876224

Sunami K, Naito Y, Komine K, Amano T, Ennishi D, Imai M, Kage H, Kanai M, Kenmotsu H, Koyama T, Maeda T, Morita S, Sakai D, Kohsaka S, Tsuchihara K, Saigusa Y, Yoshino T.
Chronological improvement in precision oncology implementation in Japan.
Cancer Sci. 2022;113:3995-4000.
PMID: 35976133

Chen Z, Zheng L, Chen Y, Liu X, Kawakami M, Mustachio LM, Roszik J, Ferry-Galow KV, Parchment RE, Liu X, Andresson T, Duncan G, Kurie JM, Rodriguez-Canales J, Liu X, Dmitrovsky E.
Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis.
Cancer Biol Ther. 2022 Dec 31;23(1):265-280.
PMID: 35387560

Naito Y, Sunami K, Kage H, Komine K, Amano T, Imai M, Koyama T, Ennishi D, Kanai M, Kenmotsu H, Maeda T, Morita S,
Sakai D, Watanabe K, Shirota H, Kinoshita I, Yoshioka M, Mamesaya N, Ito M, Kohsaka S, Saigusa Y, Yamamoto K,
Hirata M, Tsuchihara K, Yoshino T.
Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.
JAMA Netw Open. 2022;5:e2245081.
PMID: 36469316

Tamiya H, Mitani A, Abe T, Nagase Y, Suzuki H, Jo T, Tanaka G, Nagase T.
Association between Inhalation Instruction Method in Community Pharmacies and Inhaler Device Handling Error in Patients with Obstructive Lung Disease: An Evaluation of the Impact of Practical Demonstration by Pharmacists.
Biol Pharm Bull. 2022;45(12):1764
PMID: 36450529

Yoshiyasu N, Sato M, Urushiyama H, Aoyama A, Date H, Nakajima J.
Familial Interstitial Pneumonia Revealed After Living-Donor Lobar Lung Transplantation.
Ann Thorac Surg. 2021 Nov;112(5):e365-e368.
PMID: 33662313

Awano N, Jo T, Izumo T, Inomata M, Morita K, Matsui H, Fushimi K, Urushiyama H, Nagase T, Yasunaga H.
Efficacy of initial high- versus low-dose intravenous corticosteroid therapy in patients with acute exacerbation of idiopathic interstitial pneumonia: A nationwide observational study.
Ann Clin Epidemiol. 2022 Oct 26;5(2):37-47.
PMID: 38505731

Fukuda K, Matsuzaki H, Mikami Y, Makita K, Miyakawa K, Miyashita N, Hosoki K, Ishii T, Noguchi S, Urushiyama H,
Horie M, Mitani A, Yamauchi Y, Shimura E, Nakae S, Saito A, Nagase T, Hiraishi Y.
A mouse model of asthma-chronic obstructive pulmonary disease overlap induced by intratracheal papain.
Allergy. 2021 Jan;76(1):390-394.
PMID: 32740929

Isago H, Mitani A, Kohno S, Nagoshi S, Ishimori T, Saito M, Tamiya H, Miyashita N, Ishii T, Matsuzaki H, Yatomi Y,
Nagase T, Jo T.
The japanese herbal (kampo) medicine hochuekkito attenuates lung inflammation in lung emphysema.
Biol Pharm Bull. 2021;44(1):39-45.
PMID: 33390548

Ohbe H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Effect of Daikenchuto for Mechanically Ventilated Patients With Enteral Feeding Intolerance: A Propensity Score-Matched Analysis Using a Nationwide Administrative Inpatient Database.
JPEN J Parenter Enteral Nutr. 2021 Jan 22.
PMID: 33483948

Kaneko H, Itoh H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H, Yasunaga H, Komuro I.
Lipid Profile and Subsequent Cardiovascular Disease among Young Adults Aged < 50 Years.
Am J Cardiol. 2021 Mar 1;142:59-65.
PMID: 33487433

Yamana H, Iba A, Tomio J, Ono S, Jo T, Yasunaga H.
Treatment of latent tuberculosis infection in patients receiving biologic agents.
J Infect Chemother. 2021 Feb;27(2):243-249.
PMID: 33036893

Kaneko H, Itoh H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H, Yasunaga H, Komuro I.
Fasting plasma glucose and subsequent cardiovascular disease among young adults: Analysis of a nationwide epidemiological database.
Atherosclerosis. 2021 Feb;319:35-41.
PMID: 33465660

Kawakami M, Mustachio LM, Chen Y, Chen Z, Liu X, Wei CH, Roszik J, Kittai AS, Danilov AV, Zhang X, Fang B, Wang J,
Heymach JV, Tyutyunyk-Massey L, Freemantle SJ, Kurie JM, Liu X, Dmitrovsky E.
A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers.
Mol Cancer Ther. 2021 Mar;20(3):477-489.
PMID: 33277443

Katsuki R, Jo T, Yasunaga H, Kumazawa R, Uda K.
Outcomes of laparoscopic versus open pancreatoduodenectomy: A nationwide retrospective cohort study.
Surgery. 2021 Jun;169(6):1427-1434.
PMID: 33301771

Sunami K, Naito Y, Aimono E, Amano T, Ennishi D, Kage H, Kanai M, Komine K, Koyama T, Maeda T, Morita S, Sakai D, Kohsaka S, Tsuchihara K, Yoshino T.
The initial assessment of expert panel performance in core hospitals for cancer genomic medicine in Japan.
Int J Clin Oncol. 2021;26:443-449.
PMID: 33385275

Kaneko H, Itoh H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H, Yasunaga H, Komuro I.
Possible association between eating behaviors and cardiovascular disease in the general population: Analysis of a nationwide epidemiological database.
Atherosclerosis. 2021 Mar;320:79-85.
PMID: 33581389

Abe M, Mitani A, Yao A, Zhang CD, Hoshi K, Yanagimoto S.
Close association between awareness of teeth-alignment disorder and systemic disorders in late adolescence.
Healthcare (Basel) 2021;9. PMID: 33810473

Liu X, Lu Y, Chen Z, Liu X, Hu W, Zheng L, Chen Y, Kurie JM, Shi M, Mustachio LM, Adresson T, Fox S, Roszik J,
Kawakami M, Freemantle SJ, Dmitrovsky E.
The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth.
Mol Cancer Res. 2021 Apr;19(4):667-677.
PMID: 33380466

Ando T, Kawashima M, Jo T, Yasunaga H, Nagase T.
The authors reply.
Crit Care Med. 2021;49:e466-e467.
PMID: 33731626

Kiriyama H, Kaneko H, Itoh H, Kamon T, Morita K, Jo T, Fujiu K, Daimon M, Takeda N, Morita H, Yasunaga H, Komuro I.
Surgical treatment for infective endocarditis in the ageing society: a nationwide retrospective study in Japan.
Open Heart. 2021 Apr;8(1):e001627.
PMID: 33846222

Jo T, Michihata N, Yamana H, Morita K, Ishimaru M, Yamauchi Y, Hasegawa W, Urushiyama H, Uda K, Matsui H, Fushimi K, Yasunaga H, Nagase T.
Risk of drug-induced interstitial lung disease in hospitalised patients: A nested case-control study.
Thorax. 2021.
PMID: 33888574

Shinozaki N, Morita K, Matsui H, Jo T, Yasunaga H.
Semisolid vs Liquid Nutrients and 30-Day Readmission in Gastrostomy Tube-Fed Patients: A Propensity-Matched Analysis.
JPEN J Parenter Enteral Nutr. 2021 May;45(4):720-728.
PMID: 32458501

Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE,
Mascenik T, Yin WN, Barbosa Cardenas SM, O'Neal YK, Minnick CE, Chua M, Quinney NL, Gentzsch M, Anderson CW,
Ghio A, Matsui H, Nagase T, Ostrowski LE, Grubb BR, Olsen JC, Randell SH, Stripp BR, Tata PR, O'Neal WK, Boucher RC.
Secretory cells dominate airway cftr expression and function in human airway superficial epithelia.
Am J Respir Crit Care Med. 2021;203:1275-1289.
PMID: 33321047

Itoh H, Kaneko H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H, Yasunaga H, Komuro I.
Metabolically Healthy Obesity and the Risk of Cardiovascular Disease in the General Population - Analysis of a Nationwide Epidemiological Database.
Circ J. 2021 May 25;85(6):914-920.
PMID: 33551397

Huang N, Perez P, Kato T, Mikami Y, Okuda K, Gilmore RC, Conde CD, Gasmi B, Stein S, Beach M, Pelayo E, Maldonado JO, Lafont BA, Jang SI, Nasir N, Padilla RJ, Murrah VA, Maile R, Lovell W, Wallet SM, Bowman NM, Meinig SL, Wolfgang MC, Choudhury SN, Novotny M, Aevermann BD, Scheuermann RH, Cannon G, Anderson CW, Lee RE, Marchesan JT, Bush M, Freire M, Kimple AJ, Herr DL, Rabin J, Grazioli A, Das S, French BN, Pranzatelli T, Chiorini JA, Kleiner DE, Pittaluga S, Hewitt SM, Burbelo PD, Chertow D, Consortium NC-A, Oral HCA, Craniofacial Biological N, Frank K, Lee J, Boucher RC, Teichmann SA, Warner BM, Byrd KM.
SARS-CoV-2 infection of the oral cavity and saliva.
Nat Med. 2021; 27: 892-903.
PMID: 33767405

Urushiyama H, Jo T, Hasegawa W, Ando T, Sakamoto Y, Uda K, Matsui H, Fushimi K, Yasunaga H, Nagase T.
Preoperative use of pirfenidone and reduced risk of postoperative severe respiratory complications in patients with idiopathic pulmonary fibrosis: Propensity score-matched analysis using a nationwide database in Japan.
Respirology. 2021; 26: 590-596.
PMID: 33870611

Kaneko H, Yano Y, Itoh H, Morita K, Kiriyama H, Kamon T, Fujiu K, Michihata N, Jo T, Takeda N, Morita H, Node K,
Carey RM, Lima JAC, Oparil S, Yasunaga H, Komuro I.
Association of Blood Pressure Classification Using the 2017 American College of Cardiology/American Heart Association Blood Pressure Guideline With Risk of Heart Failure and Atrial Fibrillation.
Circulation. 2021 Jun 8;143(23):2244-2253.
PMID: 33886370

Manaka K, Sato J, Takeuchi M, Watanabe K, Kage H, Kawai T, Sato Y, Miyagawa T, Yamada D, Kume H, Sato S, Nagase T, Iiri T, Nangaku M, Makita N.
Immune checkpoint inhibitor combination therapies very frequently induce secondary adrenal insufficiency.
Sci Rep. 2021;11:11617.
PMID: 34078988

Mitani A, Hamada K, Yoshikawa N, Morita Y, Horie T, Inoue Y, Saito M, Ishii T, Sunohara M, Takahashi R, Emoto N, Nishimoto N, Murano Y, Okazaki S, Tateishi S, Yao A, Shimura T, Kurano M, Yatomi Y, Yanagimoto S.
Epidemiological study using IgM and IgG antibody titers against SARS-CoV-2 in The University of Tokyo, Japan (UT-CATS).
J Infect Chemother. 2021 Sep;27(9):1342-1349.
PMID: 34158239

Awano N, Jo T, Yasunaga H, Inomata M, Kuse N, Tone M, Morita K, Matsui H, Fushimi K, Nagase T, Izumo T.
Body mass index and in-hospital mortality in patients with acute exacerbation of idiopathic pulmonary fibrosis.
ERJ Open Res. 2021;7.
PMID: 34195254

Amano Y, Kage H, Tanaka G, Gonoi W, Nakai Y, Kurokawa R, Inui S, Okamoto K, Harada S, Iwabu M, Morizaki Y, Abe O, Moriya K, Nagase T.
Diagnostic prediction of COVID-19 based on clinical and radiological findings in a relatively low COVID-19 prevalence area.
Respir Investig. 2021;59:446-453.
PMID: 33865743

Tanaka G, Jo T, Tamiya H, Sakamoto Y, Hasegawa W, Matsui H, Fushimi K, Yasunaga H, Nagase T.
Factors affecting in-hospital mortality of non-tuberculous mycobacterial pulmonary disease.
BMC Infect Dis. 2021;21:698.
PMID: 34284734

Oki R, Hirakawa Y, Oda Y, Nakamura M, Honda K, Abe H, Domoto Y, Miyashita N, Nagase T, Nangaku M.
Renal-limited ANCA-associated vasculitis during erlotinib treatment for lung carcinoma.
CEN Case Rep. 2021 Jul 26.
PMID: 34309804

Matsuda K, Jo T, Miyauchi M, Toyama K, Nakazaki K, Matsui H, Fushimi K, Yasunaga H, Kurokawa M.
Difference of preventing effects of G-CSF according to age in patients with malignant lymphoma: A nation-wide analysis in Japan.
J Infect Chemother. 2021 Aug;27(8):1151-1155.
PMID: 33745811

Kobayashi K, Jo T, Mimura W, Suzukawa M, Ohshima N, Tanaka G, Akazawa M, Matsui H, Fushimi K, Yasunaga H,
Nagase T, Nagai H.
Interrupted time-series analyses of routine vaccination program for elderly pneumonia patients in japan; an ecological study using aggregated nationwide inpatient data.
Hum Vaccin Immunother. 2021:1-9.
PMID: 33877954

Ando T, Kage H, Matsumoto Y, Zokumasu K, Nagase T.
Lower dose of ethambutol may reduce ocular toxicity without radiological deterioration for Mycobacterium avium complex pulmonary disease.
Respiratory investigation. 2021.
PMID: 34389250

Kurokawa R, Inui S, Gonoi W, Nakai Y, Ishida M, Watanabe Y, Kubo T, Amano Y, Okamoto K, Kage H, Harada S, Tanaka G, Kawahara T, Nagase T, Moriya K, Abe O.
Standardized reporting systems of chest computed tomography in a population with low coronavirus disease 2019 prevalence: A retrospective comparative study.
Heliyon. 2021;7:e07743.
PMID: 34395930

Ikushima H, Hiraishi Y, Toriumi K, Ando T, Tamiya H, Ishida J, Amano Y, Kage H, Tanaka G, Nagase T.
Multiple cerebral infarctions in ROS1-rearranged lung adenocarcinoma.
Respirol Case Rep. 2021;9:e0831.
PMID: 34471540

Yokoyama A, Sakamoto Y, Jo T, Urushiyama H, Tamiya H, Tanaka G, Matsui H, Fushimi K, Yasunaga H, Nagase T.
Pulmonary disease as a risk factor for transfusion-related acute lung injury.
ERJ Open Res. 2021;7.
PMID: 34476252

Yamaguchi Y, Saito A, Horie M, Aoki A, Micke P, Ohshima M, Kappert K.
Targeting hepatocyte growth factor in epithelial-stromal interactions in an in vitro experimental model of human periodontitis.
Odontology. 2021;109(4):912-920.
PMID: 34128105

Miyashita N, Saito A.
Organ Specificity and Heterogeneity of Cancer-Associated Fibroblasts in Colorectal Cancer.
Int J Mol Sci. 2021 Oct 11;22(20):10973.
PMID: 34681633

Abe M, Mitani A, Zong L, Zhang CD, Hoshi K, Yanagimoto S.
High frequency and long duration of toothbrushing can potentially reduce the risk of common systemic diseases in late adolescence.
Spec Care Dentist 2021.
PMID: 34687071

Tamiya H, Mitani A, Isago H, Ishimori T, Saito M, Jo T, Tanaka G, Yanagimoto S, Nagase T.
Measurement of chest wall motion using a motion capture system with the one-pitch phase analysis method.
Sci Rep. 2021 Nov 2;11(1):21497
PMID: 34728740

Miyashita N, Enokido T, Horie M, Fukuda K, Urushiyama H, Strell C, Brunnström H, Micke P, Saito A, Nagase T.
TGF-β-mediated epithelial-mesenchymal transition and tumor-promoting effects in CMT64 cells are reflected in the transcriptomic signature of human lung adenocarcinoma.
Sci Rep. 2021;11:22380.
PMID: 34789779

Ando T, Kage H, Matsumoto Y, Zokumasu K, Yotsumoto T, Maemura K, Amano Y, Watanabe K, Nakajima J, Nagase T,
Takai D.
Integrin alpha11 in non-small cell lung cancer is associated with tumor progression and postoperative recurrence.
Cancer Sci. 111: 200-208; 2020.
PMID: 31778288

Ohbe H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Differences in effect of early enteral nutrition on mortality among ventilated adults with shock requiring low-, medium-, and high-dose noradrenaline: A propensity-matched analysis.
Clin Nutr. 2020;39:460-467.
PMID: 30808573

Mouri H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Effect of sugammadex on postoperative myasthenic crisis in myasthenia gravis patients: Propensity score analysis of a japanese nationwide database.
Anesth Analg. 2020;130:367-373.
PMID: 31124838

Isago H, Mitani A, Mikami Y, Horie M, Urushiyama H, Hamamoto R, Terasaki Y, Nagase T.
Epithelial expression of yap and taz is sequentially required in lung development.
Am J Respir Cell Mol Biol. 2020;62:256-266.
PMID: 31486675

Mikami Y, Jo T, Matsuzaki H, Ishimori T, Saito M, Sakamoto Y, Yamauchi Y, Takai D, Yatomi Y, Nagase T.
Preoperative intervention with long-acting bronchodilators for the reduction of postoperative pulmonary complications in untreated patients with obstructive lung disease.
Clin Respir J. 2020; 14: 92-101.
PMID: 31715066

Ohbe H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Early enteral nutrition in patients with severe traumatic brain injury: A propensity score-matched analysis using a nationwide inpatient database in japan.
Am J Clin Nutr. 2020;111:378-384.
PMID: 31751450

Jo T, Yasunaga H, Yamauchi Y, Mitani A, Hiraishi Y, Hasegawa W, Sakamoto Y, Matsui H, Fushimi K, Nagase T.
Inhaled corticosteroid withdrawal may improve outcomes in elderly patients with copd exacerbation: A nationwide database study.
ERJ Open Res. 2020;6.
PMID: 32039260

Ohbe H, Goto T, Yamazaki R, Jo T, Matsui H, Fushimi K, Yasunaga H.
Clinical trajectories of suicide attempts and self-harm in patients admitted to acute-care hospitals in japan: A nationwide inpatient database study.
J Epidemiol. 2020.
PMID: 32249268

Watanabe K, Kage H, Nagoshi S, Toyama K, Ohno Y, Shinozaki-Ushiku A, Nakazaki K, Suzuki H, Kurokawa M, Nagase T.
Dual EGFR and ABL Tyrosine Kinase Inhibitor Treatment in a Patient with Concomitant EGFR-Mutated Lung Adenocarcinoma and BCR-ABL1-Positive CML.
Case Rep Oncol Med. 2020 19;2020:4201727
PMID: 32257476

Muroyama Y, Tamiya H, Tanaka G, Tanaka W, Huang AC, Oldridge DA, Matsusaka K, Takazawa Y, Jo T, Ushiku T, Nagase T.
Alpha-fetoprotein-producing lung hepatoid adenocarcinoma with brain metastasis treated with s-1.
Case Rep Oncol. 2020;13:1552-1559.
PMID: 33564297

Oki R, Hirakawa Y, Kimura H, Honda K, Hinata M, Abe H, Domoto Y, Tanaka G, Nagase T, Nangaku M.
Renal effects after pembrolizumab treatment for non-small cell lung carcinoma.
Intern Med. 2020;59:977-981.
PMID: 31813918

Kawata M, Jo T, Taketomi S, Inui H, Yamagami R, Matsui H, Fushimi K, Yasunaga H, Tanaka S.
Type of bone graft and primary diagnosis were associated with nosocomial surgical site infection after high tibial osteotomy: Analysis of a national database.
Knee Surg Sports Traumatol Arthrosc. 2020.
PMID: 32239271

Saito M, Mitani A, Ishimori T, Miyashita N, Isago H, Mikami Y, Noguchi S, Tarui M, Nagase T.
Active mtor in lung epithelium promotes epithelial-mesenchymal transition and enhances lung fibrosis.
Am J Respir Cell Mol Biol. 2020;62:699-708.
PMID: 32208980

Mizutani E, Morita R, Emoto N, Nagai H, Moda M, Kasai S, Okochi Y, Kodama M, Abe K.
[Pancreatic Pleural Effusion;Report of a Case].
Kyobu geka The Japanese journal of thoracic surgery. 73: 476-479; 2020.
PMID: 32475977

Okunishi K, Wang H, Suzukawa M, Ishizaki R, Kobayashi E, Kihara M, Abe T, Miyazaki JI, Horie M, Saito A, Saito H,
Nakae S, Izumi T.
Exophilin-5 regulates allergic airway inflammation by controlling IL-33-mediated Th2 responses.
J Clin Invest. 2020; 130: 3919-3935.
PMID: 32240120

Dmitrovsky E, Kawakami M, Liu XI, Freemantle SJ, Kurie JM.
TRIGGERING ANAPHASE CATASTROPHE TO COMBAT ANEUPLOID CANCERS.
Trans Am Clin Climatol Assoc. 2020;131:82-94.
PMID: 32675848

Kato T, Hiraishi Y, Kaseda K, Suzuki S, Tanaka G, Yamauchi Y, Yasui M, Shinozaki-Ushiku A, Ushiku T, Yamaji O, O'Neal WK, Nagase T.
A 79-year-old man with progressive dyspnea and multiple pulmonary nodules.
Chest. 2020;158:e79-e84.
PMID: 32768080

Mouri H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Impact of glucocorticoid supplementation on reducing perioperative complications in patients on long-term glucocorticoid medication: A propensity score analysis using a nationwide inpatient database.
Am J Surg. 2020.
PMID: 32067706

Okuma HA, Yonemori K, Narita SN, Sukigara T, Hirakawa A, Shimizu T, Shibata T, Kawai A, Yamamoto N, Nakamura K, Nishida T, Fujiwara Y.
MASTER KEY Project: Powering Clinical Development for Rare Cancers Through a Platform Trial.
Clin Pharmacol Ther. 2020; 108: 596-605.
PMID: 32112563

Nilsson MB, Sun H, Robichaux J, Pfeifer M, Hofstad M, Kawakami M, Le X, Liu X, Fan Y, Poteete A, Hu L, Negrao MV,
Tran H, Dmitrovsky E, Peng D, Gibbons DL, Wang J, Heymach JV.
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components.
Sci Transl Med. 2020 Sep 2;12(559):eaaz4589.
PMID: 32878980

Kaneko H, Itoh H, Yotsumoto H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H,
Yasunaga H, Komuro I.
Association of Cancer With Outcomes in Patients Hospitalized for Heart Failure.
Circ J. 2020 Sep 25;84(10):1771-1778.
PMID: 32921679

Itoh H, Kaneko H, Kiriyama H, Kamon T, Fujiu K, Morita K, Yotsumoto H, Michihata N, Jo T, Takeda N, Morita H,
Yasunaga H, Komuro I.
Reverse J-shaped relationship between body mass index and in-hospital mortality of patients hospitalized for heart failure in Japan.
Heart Vessels. 2021 Mar;36(3):383-392.
PMID: 32980921

Yotsumoto T, Maemura K, Watanabe K, Amano Y, Matsumoto Y, Zokumasu K, Ando T, Kawakami M, Kage H, Nakajima J, Yatomi Y, Nagase T, Takai D.
NRXN1 as a novel potential target of antibody-drug conjugates for small cell lung cancer.
Oncotarget. 2020;11:3590-3600.
PMID: 33062195

Shinozaki-Ushiku A, Kohsaka S, Kage H, Oda K, Miyagawa K, Nakajima J, Aburatani H, Mano H, Ushiku T.
Genomic profiling of multiple primary cancers including synchronous lung adenocarcinoma and bilateral malignant mesotheliomas: Identification of a novel BAP1 germline variant.
Pathol Int. 2020;70:775-780.
PMID: 32583627

Ando T, Kawashima M, Jo T, Masuda K, Yamauchi Y, Tanaka G, Kage H, Suzukawa M, Nagai H, Matsui H, Fushimi K, Yasunaga H, Nagase T.
Early Arterial Embolization and Mortality in Mechanically Ventilated Patients With Hemoptysis: A Nationwide Retrospective Cohort Study.
Crit Care Med. 2020;48:1480-1486.
PMID: 32931191

Miyashita N, Horie M, Suzuki HI, Saito M, Mikami Y, Okuda K, Boucher RC, Suzukawa M, Hebisawa A, Saito A, Nagase T.
FOXL1 Regulates Lung Fibroblast Function via Multiple Mechanisms.
Am J Respir Cell Mol Biol. 2020; 63: 831-842.
PMID: 32946266

Kaneko H, Itoh H, Yotsumoto H, Kiriyama H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Takeda N, Morita H,
Yasunaga H, Komuro I.
Association of Isolated Diastolic Hypertension Based on the Cutoff Value in the 2017 American College of Cardiology/American Heart Association Blood Pressure Guidelines With Subsequent Cardiovascular Events in the General Population.
J Am Heart Assoc. 2020 Oct 20;9(19):e017963.
PMID: 32993440

Hosoki K, Mikami Y, Urushiyama H, Souma K, Kawamura G, Uchida K, Nagase T, Jo T.
Predictors of postoperative acute exacerbation of interstitial lung disease: a case-control study.
BMJ Open Respir Res. 2020; 7.
PMID: 33115770

Mizutani E, Morita R, Emoto N, Moda M, Kasai S, Okochi Y, Kodama M, Abe K.
[Multiple Minute Pulmonary Meningothelial-like Nodules;Report of a Case].
Kyobu geka The Japanese journal of thoracic surgery. 73: 968-971; 2020.
PMID: 33130727

Yamana H, Ono S, Michihata N, Jo T, Yasunaga H.
Outpatient Prescriptions of Kampo Formulations in Japan.
Intern Med. 2020 Nov 15;59(22):2863-2869.
PMID: 32713918

Ikeda Kurakawa K, Okada A, Jo T, Ono S, Bessho K, Michihata N, Matsui H, Yamaguchi S, Fushimi K, Kadowaki T, Yasunaga H.
Effects of Prophylactic Antibiotics on Length of Stay and Total Costs for Pediatric Acute Pancreatitis: A Nationwide Database Study in Japan.
Pancreas. 2020 Nov/Dec;49(10):1321-1326.
PMID: 33122520

Kaneko H, Itoh H, Kamon T, Fujiu K, Morita K, Michihata N, Jo T, Morita H, Yasunaga H, Komuro I.
Association of Cardiovascular Health Metrics With Subsequent Cardiovascular Disease in Young Adults.
J Am Coll Cardiol. 2020 Nov 17;76(20):2414-2416.
PMID: 33183514

Horie M, Castaldi A, Sunohara M, Wang H, Ji Y, Liu Y, Li F, Wilkinson TA, Hung L, Shen H, Kage H, Offringa IA, Marconett CN, Flodby P, Zhou B, Borok Z.
Integrated Single-Cell RNA-Sequencing Analysis of Aquaporin 5-Expressing Mouse Lung Epithelial Cells Identifies GPRC5A as a Novel Validated Type I Cell Surface Marker.
Cells. 2020;9:E2460.
PMID: 33187367

Papadaki V, Asada K, Watson JK, Tamura T, Leung A, Hopkins J, Dellett M, Sasai N, Davaapil H, Nik-Zainal S, Longbottom R, Nakakido M, Torii R, Veerakumarasivam A, Kaneko S, Sagoo MS, Murphy G, Mitani A, Tsumoto K, Kelly JD, Hamamoto R, Ohnuma SI.
Two secreted proteoglycans, activators of urothelial cell-cell adhesion, negatively contribute to bladder cancer initiation and progression.
Cancers (Basel). 2020;12.
PMID: 33202923

Miyashita N, Horie M, Mikami Y, Urushiyama H, Fukuda K, Miyakawa K, Matsuzaki H, Makita K, Morishita Y, Harada H, Backman M, Lindskog C, Brunnström H, Micke P, Nagase T, Saito A.
ASCL1 promotes tumor progression through cell-autonomous signaling and immune modulation in a subset of lung adenocarcinoma.
Cancer Lett. 2020; 489: 121-132.
PMID: 32534174

Okuda R, Takemura T, Mikami Y, Hagiwara E, Iwasawa T, Baba T, Kitamura H, Komatsu S, Okudela K, Ohashi K, Ogura T.
Inhalation challenge test using pigeon eggs for chronic hypersensitivity pneumonitis.
Clinical and Experimental Allergy. 2020; 50: 1381-1390.
PMID: 33010071

Takeda K, Kawashima M, Masuda K, Kimura Y, Yamamoto S, Enomoto Y, Igei H, Ando T, Narumoto O, Morio Y, Matsui H.
Long-Term Outcomes of Bronchial Artery Embolization for Patients with Non-Mycobacterial Non-Fungal Infection Bronchiectasis.
Respiration; international review of thoracic diseases. 99: 961-969; 2020.
PMID: 33264771

Kamon T, Kaneko H, Kiriyama H, Itoh H, Fujiu K, Kumazawa R, Morita K, Michihata N, Jo T, Miura M, Kodera S, Uehara M, Ando J, Inoue T, Kinoshita O, Yamauchi H, Mori Y, Nakao T, Daimon M, Takeda N, Morita H, Ono M, Yasunaga H, Komuro I.
Transcatheter Aortic Valve Implantation and Surgical Aortic Valve Replacement for Aortic Stenosis in Japan - Analysis of a Nationwide Inpatient Database.
Circ Rep. 2020 Dec 1;2(12):753-758.
PMID: 33693206

Kawakami M, Liu X, Dmitrovsky E.
New Cell Cycle Inhibitors Target Aneuploidy in Cancer Therapy.
Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:361-377.
PMID: 30110577

Mouri H, Jo T, Michihata N, Matsui H, Fushimi K, Yasunaga H.
Continuous neuromuscular blockade and mortality in subjects with exacerbation of idiopathic interstitial pneumonias.
Respir Care. 2019;64:34-39.
PMID: 30154126

Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, Noguchi S, Urushiyama H, Hiraishi Y, Mitani A,
Borok Z, Nagase T, Yamauchi Y.
Cish is a negative regulator of il-13-induced ccl26 production in lung fibroblasts.
Allergol Int. 2019;68:101-109.
PMID: 30197185

Noda-Narita S, Mizuno S, Noguchi S, Watanabe K, Nakai Y, Koike K, Kage H, Nagase T.
Development of mild drug-induced sclerosing cholangitis after discontinuation of nivolumab.
Eur J Cancer. 2019 Jan;107:93-96.
PMID: 30554074

Abe M, Watanabe K, Shinozaki-Ushiku A, Ushiku T, Abe T, Fujihara Y, Amano Y, Zong L, Wang CP, Kubo E, Inaki R, Kinoshita N, Yamashita S, Takai D, Ushijima T, Nagase T, Hoshi K.
Identification of a metastatic lung adenocarcinoma of the palate mucosa through genetic and histopathological analysis:
a rare case report and literature review.
BMC Cancer. 2019 Jan 11;19(1):52.
PMID: 30634950

Saito M, Kage H, Ando T, Sawada R, Amano Y, Goto Y, Shinoda Y, Nagase T.
Prevalence of bone pain decreases as lymph node stage increases in nonsmall cell lung cancer patients.
Curr Probl Cancer. 2019 Feb;43(1):86-91.
PMID: 30195805

Watanabe K, Kage H, Shinozaki-Ushiku A, Kohsaka S, Takai D, Nakajima J, Miyagawa K, Aburatani H, Mano H, Nagase T.
Spontaneous Transdifferentiation from Small Cell Lung Carcinoma to Squamous Cell Carcinoma.
J Thorac Oncol. 2019;14:e31-e34.
PMID: 30683296

Ota K, Sasabuchi Y, Matsui H, Jo T, Fushimi K, Yasunaga H.
Age distribution and seasonality in acute eosinophilic pneumonia: Analysis using a national inpatient database.
BMC Pulm Med. 2019;19:38.
PMID: 30755187

Ohbe H, Isogai S, Nakajima M, Jo T, Matsui H, Fushimi K, Yasunaga H.
Physician-manned prehospital emergency care in tertiary emergency centers in japan.
Acute Med Surg. 2019;6:165-172.
PMID: 30976443

Ando T, Noguchi S, Enokida T, Yamato A, Kage H, Yamauchi Y, Okazaki A, Wakabayashi Y, Moriya K, Yamauchi H, Ono M, Nagase T.
Infectious Aneurysm Caused by Citrobacter koseri in an Immunocompetent Patient.
Intern Med. 2019 Mar 15;58(6):813-816.
PMID: 30449805

Michihata N, Shigemi D, Sasabuchi Y, Matsui H, Jo T, Yasunaga H.
Safety and effectiveness of japanese herbal kampo medicines for treatment of hyperemesis gravidarum.
Int J Gynaecol Obstet. 2019;145:182-186.
PMID: 30734286

Kohsaka S, Tatsuno K, Ueno T, Nagano M, Shinozaki-Ushiku A, Ushiku T, Takai D, Ikegami M, Kobayashi H, Kage H,
Ando M, Hata K, Ueda H, Yamamoto S, Kojima S, Oseto K, Akaike K, Suehara Y, Hayashi T, Saito T, Takahashi F,
Takahashi K, Takamochi K, Suzuki K, Nagayama S, Oda Y, Mimori K, Ishihara S, Yatomi Y, Nagase T, Nakajima J,
Tanaka S, Fukayama M, Oda K, Nangaku M, Miyazono K, Miyagawa K, Aburatani H, Mano H.
Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens.
Cancer Sci. 2019;110:1464-1479.
PMID: 30737998

Ando T, Kawashima M, Masuda K, Takeda K, Okuda K, Suzuki J, Ohshima N, Horibe M, Tamura A, Nagai H, Matsui H,
Ohta K.
Exacerbation of chronic pulmonary aspergillosis was associated with a high rebleeding rate after bronchial artery embolization.
Respiratory investigation. 57: 260-267; 2019.
PMID: 30692051

Urushiyama H, Terasaki Y, Nagasaka S, Kokuho N, Endo Y, Terasaki M, Kunugi S, Makita K, Isago H, Hosoki K, Souma K, Ishii T, Matsuzaki H, Hiraishi Y, Mikami Y, Noguchi S, Tamiya H, Mitani A, Yamauchi Y, Shimizu A, Nagase T.
Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice.
J Cell Mol Med. 2019; 23: 3563-3571.
PMID: 30873733

Sakatani T, Kage H, Takayanagi S, Watanabe K, Hiraishi Y, Shinozaki-Ushiku A, Tanaka S, Ushiku T, Saito N, Nagase T.
Brain Metastasis Mimicking Brain Abscess in ALK-Positive Non-Small-Cell Lung Cancer.
Case Rep Oncol Med. 2019; 2019: 9141870.
PMID: 31316849

Noda-Narita S, Shimomura A, Kawachi A, Sumiyoshi-Okuma H, Sudo K, Shimoi T, Noguchi E, Yonemori K, Shimizu C, Fujiwara Y, Tamura K.
Comparison of the efficacy of trastuzumab emtansine between patients with metastatic human epidermal growth factor receptor 2-positive breast cancers previously treated with combination trastuzumab and pertuzumab and with trastuzumab only in Japanese population.
Breast Cancer. 2019; 26: 492-498.
PMID: 30737616

Sawai Y, Katsuya Y, Shinozaki-Ushiku A, Iwasaki A, Fukayama M, Watanabe K, Nagase T.
Rapid temporal improvement of pembrolizumab-induced pneumonitis using the anti-TNF-α antibody infliximab.
Drug Discov Ther. 2019 Jul 22;13(3):164-167.
PMID: 31257354

Saito A, Hakamata Y, Yamada Y, Sunohara M, Tarui M, Murano Y, Mitani A, Tanaka K, Nagase T, Yanagimoto S.
Pleural thickening on screening chest X-rays: a single institutional study.
Respir Res. 2019; 20: 138.
PMID: 31277661

Kage H, Kohsaka S, Shinozaki-Ushiku A, Hiraishi Y, Sato J, Nagayama K, Ushiku T, Takai D, Nakajima J, Miyagawa K, Aburatani H, Mano H, Nagase T.
Small Lung Tumor Biopsy Samples Are Feasible for High Quality Targeted Next Generation Sequencing.
Cancer Sci. 2019;47:1072-1080.
PMID: 31222846

Ohbe H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Early enteral nutrition in patients undergoing sustained neuromuscular blockade: A propensity-matched analysis using a nationwide inpatient database.
Crit Care Med. 2019;47:1072-1080.
PMID: 31306255

Zheng L, Chen Z, Kawakami M, Chen Y, Roszik J, Mustachio LM, Kurie JM, Villalobos P, Lu W, Behrens C, Mino B, Solis LM, Silvester J, Thu KL, Cescon DW, Rodriguez-Canales J, Wistuba II, Mak TW, Liu X, Dmitrovsky E.
Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy.
Mol Cancer Ther. 2019 Oct;18(10):1775-1786.
PMID: 31358662

Kumazawa R, Jo T, Matsui H, Fushimi K, Yasunaga H.
Association between angiotensin-converting enzyme inhibitors and post-stroke aspiration pneumonia.
J Stroke Cerebrovasc Dis. 2019;28:104444.
PMID: 31635965

Hiraishi Y, Jo T, Michihata N, Hasegawa W, Sakamoto Y, Urushiyama H, Matsui H, Fushimi K, Nagase T, Yasunaga H, Yamauchi Y.
Hospital volume and mortality following diagnostic bronchoscopy in lung cancer patients: Data from a national inpatient database in japan.
Respiration. 2019;97:264-272.
PMID: 30408783

Ohbe H, Isogai S, Jo T, Matsui H, Fushimi K, Yasunaga H.
Extracorporeal membrane oxygenation improves outcomes of accidental hypothermia without vital signs: A nationwide observational study.
Semin Thromb Hemost. 2019;45:760-766.
PMID: 31513865

Ohbe H, Isogai S, Jo T, Matsui H, Fushimi K, Yasunaga H.
Treatment with antithrombin or thrombomodulin and mortality from heatstroke-induced disseminated intravascular coagulation: A nationwide observational study.
Resuscitation. 2019;144:27-32.
PMID: 31627216

Goto T, Jo T, Matsui H, Fushimi K, Hayashi H, Yasunaga H.
Machine learning-based prediction models for 30-day readmission after hospitalization for chronic obstructive pulmonary disease.
Copd. 2019;16:338-343.
PMID: 31709851

Tateishi K, Ko R, Shukuya T, Okuma Y, Watanabe S, Kuyama S, Murase K, Tsukita Y, Ashinuma H, Nakagawa T,
Uematsu K, Nakao M, Mori Y, Kaira K, Mouri A, Miyabayashi T, Sakashita H, Matsumoto Y, Tanigawa T, Koizumi T, Morita S, Kobayashi K, Nukiwa T, Takahashi K; North East Japan Study Group.
Clinical Outcomes of Second-Line Chemotherapy in Patients with Previously Treated Advanced Thymic Carcinoma:
A Retrospective Analysis of 191 Patients from the NEJ023 Study.
Oncologist. 2019; 24: 1-7.
PMID: 31771990

Kage H, Flodby P, Zhou B, Borok Z.
Dichotomous roles of claudins as tumor promoters or suppressors: lessons from knockout mice.
Cell Mol Life Sci. 2019;76:4663-4672.
PMID: 31332482

Ishii T, Muroi M, Horiguchi K, Tanamoto KI, Nagase T, Yamashita N.
Activation through toll-like receptor 2 on group 2 innate lymphoid cells can induce asthmatic characteristics.
Clin Exp Allergy. 2019; 49: 1624-1632.
PMID: 31494992

Makita K, Mikami Y, Matsuzaki H, Narumoto O, Takai D, Yatomi Y, Nagase T.
Utility of bronchoscopy in the definitive diagnosis of patients with haematological malignancies presenting with radiological abnormalities.
Clin Respir J. 2018; 12: 1381-1388.
PMID: 28752537

Shinno Y, Kage H, Chino H, Inaba A, Arakawa S, Noguchi S, Amano Y, Yamauchi Y, Tanaka G, Nagase T.
Old age and underlying interstitial abnormalities are risk factors for development of ARDS after pleurodesis using limited amount of large particle size talc.
Int Arch Allergy Immunol. 2018; 175: 26-35.
PMID: 28980363

Makita K, Mikami Y, Matsuzaki H, Miyashita N, Takeshima H, Noguchi S, Horie M, Urushiyama H, Iikura M, Hojo M, Nagase T, Yamauchi Y.
Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells.
Respirology. 2018; 23: 55-59.
PMID: 29342461

Sugitani N, Gono T, Tokuda H, Takemura T, Moda M, Emoto N, Kiire-Kobayashi A, Kasai S, Okochi Y, Yamanaka H.
Progressive destructive bronchiolectasis followed by appearance of multiple pulmonary cystic lesions mimicking honeycombing in a patient with rheumatoid arthritis.
Modern Rheumatology Case Reports. 2018; 2:14–19.

Sato C, Okuda K, Tamiya H, Yamamoto K, Hoshina K, Narumoto O, Urushiyama H, Noguchi S, Amano Y, Watanabe K, Mitani A, Kage H, Tanaka G, Yamauchi Y, Takai D, Nagase T.
Acute Arterial Thrombosis during Postoperative Adjuvant Cisplatin-based Chemotherapy for Completely Resected Lung Adenocarcinoma.
Intern Med. 2018;57:557-561.
PMID: 29225246

Mustachio LM, Lu Y, Kawakami M, Roszik J, Freemantle SJ, Liu X, Dmitrovsky E.
Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target.
Cancer Res. 2018 Feb 1;78(3):587-592.
PMID: 29343520

Kawakami M, Mustachio LM, Zheng L, Chen Y, Rodriguez-Canales J, Mino B, Kurie JM, Roszik J, Villalobos PA, Thu KL, Silvester J, Cescon DW, Wistuba II, Mak TW, Liu X, Dmitrovsky E.
Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.
Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):1913-1918.
PMID: 29434041

Yanagiya M, Matsumoto J, Nagano M, Kusakabe M, Matsumoto Y, Furukawa R, Ohara S, Usui K.
Endoscopic bronchial occlusion for postoperative persistent bronchopleural fistula with computed tomography fluoroscopy guidance and virtual bronchoscopic navigation: A case report.
Medicine (Baltimore). 2018; 97: e9921.
PMID: 29443771

Ishii T, Niikura Y, Kurata K, Muroi M, Tanamoto K, Nagase T, Sakaguchi M, Yamashita N.
Time-dependent distinct roles of Toll-like receptor 4 in a house dust mite-induced asthma mouse model.
Scand J Immunol. 2018; 87.
PMID: 29337391

Zhou B, Flodby P, Luo J, Castillo DR, Liu Y, Yu FX, McConnell A, Varghese B, Li G, Chimge NO, Sunohara M, Koss MN, Elatre W, Conti P, Liebler JM, Yang C, Marconett CN, Laird-Offringa IA, Minoo P, Guan K, Stripp BR, Crandall ED, Borok Z.
Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.
J Clin Invest. 2018;3:970-984.
PMID: 29400695

Horie M, Miyashita N, Mikami Y, Noguchi S, Yamauchi Y, Suzukawa M, Fukami T, Ohta K, Asano Y, Sato S, Yamaguchi Y, Ohshima M, Suzuki HI, Saito A, Nagase T.
TBX4 is involved in the super-enhancer-driven transcriptional programs underlying features specific to lung fibroblasts.
Am J Physiol Lung Cell Mol Physiol. 2018; 314: L177-l191.
PMID: 28971975

Hiyama N, Ando T, Maemura K, Sakatani T, Amano Y, Watanabe K, Kage H, Yatomi Y, Nagase T, Nakajima J, Takai D.
Glutamate-cysteine ligase catalytic subunit is associated with cisplatin resistance in lung adenocarcinoma.
Jpn J Clin Oncol. 2018;48:303-307.
PMID: 29474642

Kawakami M, Mustachio LM, Liu X, Dmitrovsky E.
Engaging Anaphase Catastrophe Mechanisms to Eradicate Aneuploid Cancers.
Mol Cancer Ther. 2018 Apr;17(4):724-731.
PMID: 29559545

Sasabuchi Y, Matsui H, Lefor AK, Jo T, Michihata N, Fushimi K, Yasunaga H.
Japanese herbal kampo hochu-ekki-to or juzen-taiho-to after surgery for hip fracture does not reduce infectious complications.
Evid Based Complement Alternat Med. 2018;2018:8620198.
PMID: 29853976

Noda-Narita S, Sumida K, Sekine A, Hoshino J, Mise K, Suwabe T, Hayami N, Yamanouchi M, Ueno T, Mizuno H,
Kawada M, Hiramatsu R, Hasegawa E, Sawa N, Takaichi K, Ohashi K, Fujii T, Ubara Y.
TAFRO syndrome with refractory thrombocytopenia responding to tocilizumab and romiplostim: a case report.
CEN Case Rep. 2018; 7: 162-168.
PMID: 29468524

Maemura K, Kage H, Isago H, Takeshima H, Makita K, Amano Y, Takai D, Ohishi N, Nagase T.
Cerebral Arterial Air Embolism after Diagnostic Flexible Fiberoptic Bronchoscopy: A Case Report and Review of the Literature.
Case Rep Pulmonol. 2018 May 7;2018:7108215.
PMID: 29854532

Taniguchi Y, Matsumoto Y, Furukawa R, Ohara S, Usui K.
The clinical features of squamous cell lung carcinoma with sensitive EGFR mutations.
Int J Clin Oncol. 2018; 23: 452-457.
PMID: 29446042

Mitani A, Jo T, Yasunaga H, Sakamoto Y, Hasegawa W, Urushiyama H, Yamauchi Y, Matsui H, Fushimi K, Nagase T.
Venous thromboembolic events in patients with lung cancer treated with cisplatin-based versus carboplatin/nedaplatin-based chemotherapy.
Anticancer Drugs. 2018;29:560-564.
PMID: 29570101

Kage H, Kohsaka S, Shinozaki-Ushiku A, Ushiku T, Takai D, Nakajima J, Miyagawa K, Aburatani H, Mano H, Nagase T.
Spontaneous Transformation from EGFR and ALK Wild-Type Lung Adenocarcinoma to Neuroendocrine Carcinoma.
J Thorac Oncol. 2018;13:e126-e128.
PMID: 29935853

Ando T, Kage H, Saito M, Amano Y, Goto Y, Nakajima J, Nagase T.
Early stage non-small cell lung cancer patients need brain imaging regardless of symptoms.
Int J Clin Oncol. 2018;23:641-646.
PMID: 29484515

Ohbe H, Jo T, Yamana H, Matsui H, Fushimi K, Yasunaga H.
Early enteral nutrition for cardiogenic or obstructive shock requiring venoarterial extracorporeal membrane oxygenation:
A nationwide inpatient database study.
Intensive Care Med. 2018;44:1258-1265.
PMID: 30030574

Saito A, Horie M, Nagase T.
TGF-β Signaling in Lung Health and Disease.
Int J Mol Sci. 2018; 19.
PMID: 30127261

Urushiyama H, Jo T, Yasunaga H, Michihata N, Yamana H, Matsui H, Hasegawa W, Hiraishi Y, Mitani A, Fushimi K,
Nagase T, Yamauchi Y.
Effect of Hangeshashin-To (Japanese Herbal Medicine Tj-14) on Tolerability of Irinotecan: Propensity Score and Instrumental Variable Analyses.
J Clin Med. 2018; 7.
PMID: 30154384

Antonio VAA, Ono N, Saito A, Sato T, Altaf-Ul-Amin M, Kanaya S.
Classification of lung adenocarcinoma transcriptome subtypes from pathological images using deep convolutional networks.
International Journal of Computer Assisted Radiology and Surgery. 2018; 13: 1905-1913.
PMID: 30159833

Yokoyama A, Kage H, Ohama Y, Sato T, Miyashita N, Noguchi S, Okugawa S, Yamauchi Y, Moriya K, Nagase T.
Mycobacterium heckeshornense lung infection diagnosed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
J Infect Chemother. 2018;24:763-765.
PMID: 29503226

Hiyama N, Sasabuchi Y, Jo T, Hirata T, Osuga Y, Nakajima J, Yasunaga H.
The three peaks in age distribution of females with pneumothorax: A nationwide database study in japan.
Eur J Cardiothorac Surg. 2018;54:572-578.
PMID: 29596692

Jo T, Yasunaga H, Michihata N, Sasabuchi Y, Hasegawa W, Takeshima H, Sakamoto Y, Matsui H, Fushimi K, Nagase T, Yamauchi Y.
Influence of parkinsonism on outcomes of elderly pneumonia patients.
Parkinsonism Relat Disord. 2018;54:25-29.
PMID: 29627432

Ohbe H, Jo T, Matsui H, Fushimi K, Yasunaga H.
Cholinergic crisis caused by cholinesterase inhibitors: A retrospective nationwide database study.
J Med Toxicol. 2018;14:237-241.
PMID: 29907949

Nakaharai K, Morita K, Jo T, Matsui H, Fushimi K, Yasunaga H.
Early prophylactic antibiotics for severe acute pancreatitis: A population-based cohort study using a nationwide database in japan.
J Infect Chemother. 2018;24:753-758.
PMID: 29909051

Jansing NL, McClendon J, Kage H, Sunohara M, Alvarez JR, Borok Z, Zemans RL.
Isolation of Rat and Mouse Alveolar Type II Epithelial Cells.
Methods Mol Biol. 2018;1809:69-82.
PMID: 29987783

Chen L, Diao L, Yang Y, Yi X, Rodriguez BL, Li Y, Villalobos PA, Skoulidis F, Peng W, Carter BW, Rodriguez-Canales J, Kawakami M, Byers LA, Woodman SE, Papadimitrakopoulou VA, Dmitrovsky E, Wang J, Ullrich SE, Wistuba II,
Heymach JV, Qin FX, Gibbons DL.
CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.
Cancer Discov. 2018 Sep;8(9):1156-1175.
PMID: 30012853

Watanabe K, Yasumoto A, Amano Y, Kage H, Goto Y, Yatomi Y, Takai D, Nagase T.
Mean platelet volume and lymphocyte-to-monocyte ratio are associated with shorter progression-free survival in EGFR-mutant lung adenocarcinoma treated by EGFR tyrosine kinase inhibitor.
PLoS One. 2018 Sep. 7;13(9):e0203625.
PMID: 30192878

Takeshima H, Horie M, Mikami Y, Makita K, Miyashita N, Matsuzaki H, Noguchi S, Urushiyama H, Hiraishi Y, Mitani A, Borok Z, Nagase T, Yamauchi Y.
Cish is a negative regulator of il-13-induced ccl26 production in lung fibroblasts.
Allergol Int. 2018.
PMID: 30197185

Horie M, Miyashita N, Mattsson JSM, Mikami Y, Sandelin M, Brunnström H, Micke P, Nagase T, Saito A.
An integrative transcriptome analysis reveals a functional role for thyroid transcription factor-1 in small cell lung cancer.
J Pathol. 2018; 246: 154-165.
PMID: 29876935

Maemura K, Watanabe K, Ando T, Hiyama N, Sakatani T, Amano Y, Kage H, Nakajima J, Yatomi Y, Nagase T, Takai D.
Altered editing level of microRNAs is a potential biomarker in lung adenocarcinoma.
Cancer Sci. 2018;109:3326-3335.
PMID: 30022565

Urushiyama H, Jo T, Yasunaga H, Michihata N, Matsui H, Hasegawa W, Takeshima H, Sakamoto Y, Hiraishi Y, Mitani A, Fushimi K, Nagase T, Yamauchi Y.
Oral fluorouracil vs vinorelbine plus cisplatin as adjuvant chemotherapy for stage II-IIIA non-small cell lung cancer: Propensity score-matched and instrumental variable analyses.
Cancer Med. 2018; 7: 4863-4869.
PMID: 30151905

Ando T, Kawashima M, Matsui H, Takeda K, Sato R, Ohshima N, Nagai H, Kitani M, Hebisawa A, Ohta K.
Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis.
Respiration; international review of thoracic diseases. 96: 507-513; 2018.
PMID: 30286448

Miyashita N, Horie M, Suzuki HI, Yoshihara M, Djureinovic D, Persson J, Brunnström H, Lindskog C, Elfving H, Micke P, Saito A, Nagase T.
An Integrative Analysis of Transcriptome and Epigenome Features of ASCL1-Positive Lung Adenocarcinomas.
J Thorac Oncol. 2018; 13: 1676-1691.
PMID: 30121393

Hiraishi Y, Izumo T, Sasada S, Matsumoto Y, Nakai T, Tsuchida T, Baba H.
Factors affecting bacterial culture positivity in specimens from bronchoscopy in patients with suspected lung cancer.
Respir Investig. 2018; 56: 457-463.
PMID: 30392535

Hiraishi Y, Jo T, Michihata N, Hasegawa W, Sakamoto Y, Urushiyama H, Matsui H, Fushimi K, Nagase T, Yasunaga H, Yamauchi Y.
Hospital Volume and Mortality following Diagnostic Bronchoscopy in Lung Cancer Patients: Data from a National Inpatient Database in Japan.
Respiration. 2019; 97: 264-272.
PMID: 30408783

Souma K, Shichino S, Hashimoto S, Ueha S, Tsukui T, Nakajima T, Suzuki HI, Shand FHW, Inagaki Y, Nagase T, Matsushima K.
Lung fibroblasts express a miR-19a-19b-20a sub-cluster to suppress TGF-β-associated fibroblast activation in murine pulmonary fibrosis.
Sci Rep. 2018; 8: 16642.
PMID: 30413725

Saito A, Horie M, Micke P, Nagase T.
The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis.
Int J Mol Sci. 2018; 19.
PMID: 30445777

Tamiya H, Mitani A, Saito A, Ishimori T, Saito M, Isago H, Jo T, Yamauchi Y, Tanaka G, Nagase T.
Exosomal microrna expression profiling in patients with lung adenocarcinoma-associated malignant pleural effusion.
Anticancer Res. 2018;38:6707-6714.
PMID: 30504380

Hiraishi Y, Yamaguchi S, Yoshizaki T, Nambu A, Shimura E, Takamori A, Narushima S, Nakanishi W, Asada Y, Numata T, Suzukawa M, Yamauchi Y, Matsuda A, Arae K, Morita H, Hoshino T, Suto H, Okumura K, Matsumoto K, Saito H, Sudo K, Iikura M, Nagase T, Nakae S.
IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation.
Sci Rep. 2018; 8: 18052.
PMID: 30575775

Jo T, Michihata N, Yamana H, Sasabuchi Y, Matsui H, Urushiyama H, Mitani A, Yamauchi Y, Fushimi K, Nagase T,
Yasunaga H.
Reduction in exacerbation of copd in patients of advanced age using the japanese kampo medicine dai-kenchu-to: A retrospective cohort study.
Int J Chron Obstruct Pulmon Dis. 2019;14:129-139.
PMID: 30643399

Mitani A. Chronic obstructive pulmonary disease. In: Gellman M, Turner JR, editors.
Encyclopedia of behavioral medicine.
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Flodby P, Liebler JM, Sunohara M, Castillo DR, McConnell AM, Krishnaveni MS, Banfalvi A, Li M, Stripp B, Zhou B,
Crandall ED, Minoo P, Borok Z.
Region-specific role for Pten in maintenance of epithelial phenotype and integrity.
Am J Physiol Lung Cell Mol Physiol. 2017;1:L131-142.
PMID: 27864284

Mustachio LM, Kawakami M, Lu Y, Rodriguez-Canales J, Mino B, Behrens C, Wistuba I, Bota-Rabassedas N, Yu J, Lee JJ, Roszik J, Zheng L, Liu X, Freemantle SJ, Dmitrovsky E.
The ISG15-specific protease USP18 regulates stability of PTEN.
Oncotarget. 2017 Jan 3;8(1):3-14.
PMID: 27980214

Sakamoto Y, Yamauchi Y, Yasunaga H, Takeshima H, Hasegawa W, Jo T, Matsui H, Fushimi K, Nagase T.
Guidelines-concordant empiric antimicrobial therapy and mortality in patients with severe community-acquired pneumonia requiring mechanical ventilation.
Respir Investig. 2017;55:39-44.
PMID: 28012492

Kido Y, Mitani A, Isago H, Takeshima H, Narumoto O, Tanaka G, Yamauchi Y, Takai D, Ohishi N, Nagase T.
Successful treatment of pulmonary injury after nitrogen oxide exposure with corticosteroid therapy: A case report and review of the literature.
Respir Med Case Rep. 2017;20:107-110.
PMID: 28138425

Noguchi S, Saito A, Mikami Y, Urushiyama H, Horie M, Matsuzaki H, Takeshima H, Makita K, Miyashita N, Mitani A, Jo T, Yamauchi Y, Terasaki Y, Nagase T.
TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts.
Sci Rep. 2017; 7: 42595.
PMID: 28195168

Arakawa S, Kage H, Chino H, Hinata M, Hayashi A, Toya T, Noguchi S, Ushiku T, Yamauchi Y, Kurokawa M, Fukayama M, Nagase T.
Reversion of serum VZV-IgG antibody preceding disseminated visceral varicella zoster after hematopoietic stem cell transplantation.
Ann Hematol. 2017; 96:529-530.
PMID: 27844105

Matsui H, Jo T, Fushimi K, Yasunaga H.
Outcomes after early and delayed rehabilitation for exacerbation of chronic obstructive pulmonary disease: A nationwide retrospective cohort study in japan.
Respir Res. 2017;18:68.
PMID: 28431501

Marconett CN, Zhou B, Sunohara M, Pouldar TM, Wang H, Liu Y, Rieger ME, Tran E, Flodby P, Siegmund KD, Crandall ED, Laird-Offringa IA, Borok Z.
Cross-Species Transcriptome Profiling Identifies New Alveolar Epithelial Type I Cell-Specific Genes.
Am J Respir Cell Mol Biol. 2017;3:310-321.
PMID: 27749084

Suzuki HI, Katsura A, Mihira H, Horie M, Saito A, Miyazono K.
Regulation of TGF-beta-mediated endothelial-mesenchymal transition by microRNA-27.
J Biochem. 2017; 161: 417-420.
PMID: 28338957

Ishii T, Hosoki K, Nikura Y, Yamashita N, Nagase T, Yamashita N.
IFN Regulatory Factor 3 Potentiates Emphysematous Aggravation by Lipopolysaccharide.
J Immunol. 2017; 198: 3637-3649.
PMID: 28363903

Ando T, Kawashima M, Masuda K, Takeda K, Okuda K, Suzuki J, Ohshima N, Matsui H, Tamura A, Nagai H, Akagawa S, Ohta K.
Clinical and Angiographic Characteristics of 35 Patients With Cryptogenic Hemoptysis.
Chest. 152: 1008-1014; 2017.
PMID: 28526654

Sakamoto Y, Yamauchi Y, Yasunaga H, Takeshima H, Hasegawa W, Jo T, Sasabuchi Y, Matsui H, Fushimi K, Nagase T.
Development of a nomogram for predicting in-hospital mortality of patients with exacerbation of chronic obstructive pulmonary disease.
Int J Chron Obstruct Pulmon Dis. 2017;12:1605-1611.
PMID: 28615933

Sakatani T, Maemura K, Hiyama N, Amano Y, Watanabe K, Kage H, Fukayama M, Nakajima J, Yatomi Y, Nagase T, Takai D.
High expression of IRE1 in lung adenocarcinoma is associated with a lower rate of recurrence.
Jpn J Clin Oncol. 2017; 47: 543-550.
PMID: 28334878

Kawakami M, Mustachio LM, Rodriguez-Canales J, Mino B, Roszik J, Tong P, Wang J, Lee JJ, Myung JH, Heymach JV, Johnson FM, Hong S, Zheng L, Hu S, Villalobos PA, Behrens C, Wistuba I, Freemantle S, Liu X, Dmitrovsky E.
Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer.
J Natl Cancer Inst. 2017 Jun 1;109(6):djw297.
PMID: 28376145

Saito A, Horie M, Ejiri K, Aoki A, Katagiri S, Maekawa S, Suzuki S, Kong S, Yamauchi T, Yamaguchi Y, Izumi Y, Ohshima M.
MicroRNA profiling in gingival crevicular fluid of periodontitis-a pilot study.
FEBS Open Bio. 2017; 7: 981-994.
PMID: 28680811

Mustachio LM, Lu Y, Tafe LJ, Memoli V, Rodriguez-Canales J, Mino B, Villalobos PA, Wistuba I, Katayama H, Hanash SM, Roszik J, Kawakami M, Cho KJ, Hancock JF, Chinyengetere F, Hu S, Liu X, Freemantle SJ, Dmitrovsky E.
Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer.
Mol Cancer Res. 2017 Jul;15(7):905-914.
PMID: 28242811

Hasegawa W, Yamauchi Y, Yasunaga H, Takeshima H, Sakamoto Y, Jo T, Sasabuchi Y, Matsui H, Fushimi K, Nagase T.
Prognostic nomogram for inpatients with asthma exacerbation.
BMC Pulm Med. 2017;17:108.
PMID: 28778188

Matsuki R, Okuda K, Mitani A, Yamauchi Y, Tanaka G, Kume H, Homma Y, Hinata M, Hayashi A, Shibahara J, Fukayama M, Nagase T.
A case of delayed exacerbation of interstitial lung disease after discontinuation of temsirolimus.
Respir Med Case Rep. 2017;22:158-163.
PMID: 28840097

Matsumoto Y, Miura T, Horiuchi H, Usui K.
The Successful Treatment of Pulmonary Pleomorphic Carcinoma with Pembrolizumab: A Case Report.
Case Rep Oncol. 2017; 10: 752-757.
PMID: 28878661

Mitani A, Azam A, Vuppusetty C, Ito K, Mercado N, Barnes PJ.
Quercetin restores corticosteroid sensitivity in cells from patients with chronic obstructive pulmonary disease.
Exp Lung Res. 2017;43:417-425.
PMID: 29227717

Urushiyama H, Jo T, Yasunaga H, Yamauchi Y, Matsui H, Hasegawa W, Takeshima H, Hiraishi Y, Mitani A, Fushimi K, Nagase T.
Adjuvant chemotherapy versus chemoradiotherapy for small cell lung cancer with lymph node metastasis: a retrospective observational study with use of a national database in Japan.
BMC Cancer. 2017; 17: 613.
PMID: 28865438

Horie M, Kaczkowski B, Ohshima M, Matsuzaki H, Noguchi S, Mikami Y, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Hayashizaki Y, Forrest ARR, Takai D, Yamaguchi Y, Micke P, Saito A, Nagase T.
Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC.
Mol Cancer Res. 2017; 15: 1354-1365.
PMID: 28698358

Matsumoto Y, Ohara S, Furukawa R, Usui K.
The Prognosis of Small Cell Lung Cancer in Patients with Pulmonary Fibrosis.
Anticancer Res. 2017; 37: 5791-5795.
PMID: 28982903

Jo T, Yasunaga H, Sasabuchi Y, Michihata N, Morita K, Yamauchi Y, Hasegawa W, Takeshima H, Sakamoto Y, Matsui H, Fushimi K, Nagase T.
Association between dementia and discharge status in patients hospitalized with pneumonia.
BMC Pulm Med. 2017;17:128.
PMID: 28985724

Mitani A, Hakamata Y, Hosoi M, Horie M, Murano Y, Saito A, Yanagimoto S, Tsuji S, Yamamoto K, Nagase T.
The incidence and risk factors of asymptomatic primary spontaneous pneumothorax detected during health check-ups.
BMC Pulm Med. 2017;17:177.
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Mitani A. Lung function. In: Gellman M, Turner JR, editors.
Encyclopedia of behavioral medicine.
New York, NY: Springer New York; 2017. p. 1-2.

Mitani A, Ito K, Vuppusetty C, Barnes PJ, Mercado N.
Restoration of corticosteroid sensitivity in chronic obstructive pulmonary disease by inhibition of mammalian target of rapamycin.
Am J Respir Crit Care Med. 2016;193:143-153.
PMID: 26426522

Horie M, Tamiya H, Goto Y, Suzuki M, Matsuzaki H, Hasegawa WT, Noguchi S, Kawakami M, Matsuta K, Nagase T, Sakamoto Y.
Nonspecific elevation of serum Aspergillus galactomannan antigen levels in patients with rheumatoid arthritis.
Respir Investig. 2016; 54: 44-49.
PMID: 26718144

Okuda K, Masuda K, Kawashima M, Ando T, Koyama K, Ohshima N, Tamura A, Nagai H, Akagawa S, Matsui H, Ohta K.
Bronchial artery embolization to control hemoptysis in patients with Mycobacterium avium complex.
Respiratory investigation. 54: 50-58; 2016.
PMID: 26718145

Takeda K, Suzuki J, Nagai H, Watanabe K, Yokoyama A, Ando T, Suzuki J, Ohshima N, Masuda K, Tamura A, Akagawa S, Kitani M, Hebisawa A, Matsui H, Kobayashi N, Maruyama H, Ohta K.
Thoracoscopic examination of empyema in a patient with sparganosis mansoni.
J Infect Chemother. 22: 120-123; 2016.
PMID: 26603428

Ishikawa R, Amano Y, Kawakami M, Sunohara M, Watanabe K, Kage H, Ohishi N, Yatomi Y, Nakajima J, Fukayama M, Nagase T, Takai D.
The chimeric transcript RUNX1-GLRX5: a biomarker for good postoperative prognosis in Stage IA non-small-cell lung cancer.
Jpn J Clin Oncol. 2016; 46:185-189.
PMID: 26685324

Ohshima M, Yamaguchi Y, Ambe K, Horie M, Saito A, Nagase T, Nakashima K, Ohki H, Kawai T, Abiko Y, Micke P,
Kappert K.
Fibroblast VEGF-receptor 1 expression as molecular target in periodontitis.
Journal of Clinical Periodontology. 2016; 43: 128-137.
PMID: 26932322

Takeda K, Ohshima N, Nagai H, Sato R, Ando T, Kusaka K, Kawashima M, Masuda K, Matsui H, Aono A, Chikamatsu K, Mitarai S, Ohta K.
Six Cases of Pulmonary Mycobacterium shinjukuense Infection at a Single Hospital.
Internal medicine. 55: 787-791; 2016.
PMID: 27041166

Rieger ME, Zhou B, Solomon N, Sunohara M, Li C, Nguyen C, Liu Y, Pan JH, Minoo P, Crandall ED, Brody SL, Kahn M, Borok Z.
p300/β-Catenin Interactions Regulate Adult Progenitor Cell Differentiation Downstream of WNT5a/Protein Kinase C (PKC).
J Biol Chem. 2016;12:6569-82.
PMID: 26833564

Okuda K, Noguchi S, Narumoto O, Ikemura M, Yamauchi Y, Tanaka G, Takai D, Fukayama M, Nagase T.
A case of meigs' syndrome with preceding pericardial effusion in advance of pleural effusion.
BMC Pulm Med. 2016;16:71.
PMID: 27160723

Kibinge N, Ono N, Horie M, Sato T, Sugiura T, Altaf-Ul-Amin M, Saito A, Kanaya S.
Integrated pathway-based transcription regulation network mining and visualization based on gene expression profiles.
J Biomed Inform. 2016; 61: 194-202.
PMID: 27064123

Mikami Y, Matsuzaki H, Takeshima H, Makita K, Yamauchi Y, Nagase T.
Development of an In Vitro Assay to Evaluate Contractile Function of Mesenchymal Cells that Underwent Epithelial-Mesenchymal Transition.
J Vis Exp. 2016.
PMID: 27340759

Yamauchi Y, Yasunaga H, Hasegawa W, Sakamoto Y, Takeshima H, Jo T, Matsui H, Fushimi K, Nagase T.
Effect of outpatient therapy with inhaled corticosteroids on decreasing in-hospital mortality from pneumonia in patients with COPD.
Int J Chron Obstruct Pulmon Dis. 2016; 11: 1403-1411.
PMID: 27382276

Djureinovic D, Hallstrom BM, Horie M, Mattsson JSM, La Fleur L, Fagerberg L, Brunnstrom H, Lindskog C, Madjar K, Rahnenfuhrer J, Ekman S, Stahle E, Koyi H, Branden E, Edlund K, Hengstler JG, Lambe M, Saito A, Botling J, Ponten F, Uhlen M, Micke P.
Profiling cancer testis antigens in non-small-cell lung cancer.
JCI Insight. 2016; 1: e86837.
PMID: 27699219

Flodby P, Kim YH, Beard LL, Gao D, Ji Y, Kage H, Liebler JM, Minoo P, Kim KJ, Borok Z, Crandall ED.
Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance.
Am J Respir Cell Mol Biol. 2016; 55: 395-406.
PMID: 27064541

Horie M, Yamaguchi Y, Saito A, Nagase T, Lizio M, Itoh M, Kawaji H, Lassmann T, Carninci P, Forrest AR, Hayashizaki Y, Suzutani T, Kappert K, Micke P, Ohshima M.
Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis.
Sci Rep. 2016; 6: 33666.
PMID: 27645561

Yamauchi Y, Yasunaga H, Sakamoto Y, Hasegawa W, Takeshima H, Urushiyama H, Jo T, Matsui H, Fushimi K, Nagase T.
Mortality associated with bone fractures in COPD patients.
Int J Chron Obstruct Pulmon Dis. 2016; 11: 2335-2340.
PMID: 27703343

Chino H, Amano Y, Yamauchi Y, Matsuda J, Takeda N, Tanaka G, Takai D, Nagase T.
Cardiogenic syncope possibly related to bevacizumab-containing combination chemotherapy for advanced non-small cell lung cancer.
J Thorac Dis. 2016;8:2646-2650.
PMID: 27747019

Noda S, Kanda S.
Addressing epidermal growth factor receptor tyrosine kinase inhibitor resistance in non-small cell lung cancer.
Expert Rev Respir Med. 2016; 10: 547-556.
PMID: 26959310

Danilov AV, Hu S, Orr B, Godek K, Mustachio LM, Sekula D, Liu X, Kawakami M, Johnson FM, Compton DA, Freemantle SJ, Dmitrovsky E.
Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2.
Mol Cancer Ther. 2016 Nov;15(11):2758-2766.
PMID: 27550941

Kage H, Goto Y, Amano Y, Makita K, Isago H, Kobayashi K, Narumoto O, Okudaira R, Tanaka G, Takami K, Ohishi N, Nagase, T.
Development of pulmonary artery aneurysms due to Behcet’s disease and resolution after treatment.
Intern Med. 2016; 55: 3337-3340.
PMID: 27853079

Horie M, Saito A, Ohshima M, Suzuki HI, Nagase T.
YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.
Cancer Sci. 2016; 107: 1755-1766.
PMID: 27627196

Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, Fushimi K, Takami K, Nagase T.
Clinical features of 280 hospitalized patients with lymphangioleiomyomatosis in japan.
Respirology. 2015;20:160-165.
PMID: 25385157

Yoshida Y, Kage H, Murakawa T, Sato Y, Ota S, Fukayama M, Nakajima J.
Worse Prognosis for Stage IA Lung Cancer Patients with Smoking History and More Severe Chronic Obstructive Pulmonary Disease.
Ann Thorac Cardiovasc Surg. 2015; 21: 194-200.
PMID: 25641032

Tamiya H, Ochiai E, Kikuchi K, Yahiro M, Toyotome T, Watanabe A, Yaguchi T, Kamei K.
Secondary metabolite profiles and antifungal drug susceptibility of aspergillus fumigatus and closely related species, aspergillus lentulus, aspergillus udagawae, and aspergillus viridinutans.
J Infect Chemother. 2015;21:385-391.
PMID: 25737146

Amano Y, Ishikawa R, Sakatani T, Ichinose J, Sunohara M, Watanabe K, Kage H, Nakajima J, Nagase T, Ohishi N, Takai D.
Oncogenic TPM3-ALK activation requires dimerization through the coiled-coil structure of TPM3.
Biochem Biophys Res Commun. 2015; 457: 457-60.
PMID: 25596129

Horie M, Saito A, Yamaguchi Y, Ohshima M, Nagase T.
Three-dimensional Co-culture model for tumor-stromal interaction.
J Vis Exp. 2015.
PMID: 25741617

Ishibashi F, Sunohara M, Kawagoe S.
Performance of severity scores for home care-based patients suffering from pneumonia.
Geriatr Gerontol Int. 2015; 15: 311-7.
PMID: 24617550

Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, Fushimi K, Takami K, Nagase T.
Factors that predict in-hospital mortality in eosinophilic granulomatosis with polyangiitis.
Allergy 2015;70:585-590.
PMID: 25703656

Koyama K, Ohshima N, Suzuki J, Kawashima M, Takeda K, Ando T, Sato R, Nagai H, Matsui H, Ohta K.
Recurrence of chronic pulmonary aspergillosis after discontinuation of maintenance treatment by antifungal triazoles.
J Infect Chemother. 2014; 20: 375-9.
PMID: 24679654

Ishii T, Goto Y, Matsuzaki H, Ohishi N, Sakamoto Y, Saito R, Matsusaka K, Shibahara J, Nagase T.
Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma.
Intern Med. 2015; 54: 1389-1392.
PMID: 26027993

Yamauchi Y, Yasunaga H, Matsui H, Hasegawa W, Jo T, Takami K, Fushimi K, Nagase T.
Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.
BMC Pulm Med. 2015;15:69.
PMID: 26152178

Tadashi K, Masafumi H, Yasuhiro Y, Satoshi N, Yu M.
PM2.5: Role of Oxidative Stress in Health Effects and Prevention Strategy.
Nova Science Publisher

Yamauchi Y, Yasunaga H, Matsui H, Hasegawa W, Jo T, Takami K, Fushimi K, Nagase T.
Comparison of in-hospital mortality in patients with COPD, asthma and asthma-COPD overlap exacerbations.
Respirology. 2015; 20: 940-946.
PMID: 25998444

Urushiyama H, Terasaki Y, Nagasaka S, Terasaki M, Kunugi S, Nagase T, Fukuda Y, Shimizu A.
Role of α1 and α2 chains of type IV collagen in early fibrotic lesions of idiopathic interstitial pneumonias and migration of lung fibroblasts.
Lab Invest. 2015; 95: 872-885.
PMID: 26006016

Watanabe K, Amano Y, Ishikawa R, Sunohara M, Kage H, Ichinose J, Sano A, Nakajima J, Fukayama M, Yatomi Y, Nagase T, Ohishi N, Takai D.
Histone methylation-mediated silencing of miR-139 enhances invasion of non-small-cell lung cancer.
Cancer Med. 2015; 4: 1573-82.
PMID: 26256448

Saito A, Nagase T.
Hippo and TGF-β interplay in the lung field.
Am J Physiol Lung Cell Mol Physiol. 2015; 309: L756-767.
PMID: 26320155

Matsuzaki H, Mikami Y, Makita K, Takeshima H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y.
Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells.
PLoS One. 2015; 10: e0141746.
PMID: 26505478

Hu S, Lu Y, Orr B, Godek K, Mustachio LM, Kawakami M, Sekula D, Compton DA, Freemantle S, Dmitrovsky E.
Specific CP110 Phosphorylation Sites Mediate Anaphase Catastrophe after CDK2 Inhibition: Evidence for Cooperation with USP33 Knockdown.
Mol Cancer Ther. 2015 Nov;14(11):2576-85.
PMID: 26304236

Chinyengetere F, Sekula DJ, Lu Y, Giustini AJ, Sanglikar A, Kawakami M, Ma T, Burkett SS, Eisenberg BL, Wells WA,
Hoopes PJ, Demicco EG, Lazar AJ, Torres KE, Memoli V, Freemantle SJ, Dmitrovsky E.
Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas.
BMC Cancer. 2015 Nov 10;15:886.
PMID: 26555296

Noguchi S, Yamauchi Y, Takizawa H.
Novel therapeutic strategies for fibrotic lung disease: a review with a focus on epithelial-mesenchymal transition.
Recent Pat Inflamm Allergy Drug Discov. 2014; 8: 9-18.
PMID: 24383438

Risse PA, Lavoie-Lamoureux A, Jo T, Tsuchiya K, Siddiqui S, Martin JG.
Airway arginase expression and nomega-hydroxy-nor-arginine effect on methacholine-induced bronchoconstriction differentiate lewis and fischer rat strains.
J Appl Physiol (1985). 2014;116:621-627.
PMID: 24505101

Hirota N, McCuaig S, O'Sullivan MJ, Martin JG.
Serotonin augments smooth muscle differentiation of bone marrow stromal cells.
Stem Cell Res. 2014; 12: 599-609.
PMID: 24595007

Koyama K, Ohshima N, Suzuki J, Kawashima M, Takeda K, Ando T, Sato R, Nagai H, Matsui H, Ohta K.
Recurrence of chronic pulmonary aspergillosis after discontinuation of maintenance treatment by antifungal triazoles.
J Infect Chemother. 20: 375-379; 2014.
PMID: 24679654

Horie M, Saito A, Yamauchi Y, Mikami Y, Sakamoto M, Jo T, Nakajima J, Takizawa H, Nagase T, Kohyama T.
Histamine induces human lung fibroblast-mediated collagen gel contraction via histamine H1 receptor.
Exp Lung Res. 2014; 40: 222-236.
PMID: 24809793

Kassai H, Sugaya Y, Noda S, Nakao K, Maeda T, Kano M, Aiba A.
Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases.
Cell Rep. 2014; 7: 1626-1639.
PMID: 24857653

Tarui M, Shindou H, Kumagai K, Morimoto R, Harayama T, Hashidate T, Kojima H, Okabe T, Nagano T, Nagase T,
Shimizu T.
Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2.
J Lipid Res. 2014; 55: 1386-1396.
PMID: 24850807

Li G, Flodby P, Luo J, Kage H, Sipos A, Gao D, Ji Y, Beard LL, Marconett CN, Demaio L, Kim YH, Kim KJ, Laird-Offringa IA, Minoo P, Liebler JM, Zhou B, Crandall ED, Borok Z.
Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis.
Am J Respir Cell Mol Biol. 2014; 51: 210-22.
PMID: 24588076

Kage H, Flodby P, Gao D, Kim YH, Marconett CN, DeMaio L, Kim KJ, Crandall ED, Borok Z.
Claudin 4 knockout mice: normal physiological phenotype with increased susceptibility to lung injury.
Am J Physiol Lung Cell Mol Physiol. 2014; 307: L524-36.
PMID: 25106430

Horie M, Saito A, Noguchi S, Yamaguchi Y, Ohshima M, Morishita Y, Suzuki HI, Kohyama T, Nagase T.
Differential knockdown of TGF-β ligands in a three-dimensional co-culture tumor- stromal interaction model of lung cancer.
BMC Cancer. 2014; 14: 580.
PMID: 25107280

Noguchi S, Saito A, Horie M, Mikami Y, Suzuki HI, Morishita Y, Ohshima M, Abiko Y, Mattsson JS, König H, Lohr M,
Edlund K, Botling J, Micke P, Nagase T.
An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.
Clin Cancer Res. 2014; 20: 4660-4672.
PMID: 24951773

Ichinose J, Watanabe K, Sano A, Nagase T, Nakajima J, Fukayama M, Yatomi Y, Ohishi N, Takai D.
Alternative polyadenylation is associated with lower expression of PABPN1 and poor prognosis in non-small cell lung cancer.
Cancer Sci. 2014; 105: 1135-41.
PMID: 24975429

Hasegawa W, Yamauchi Y, Yasunaga H, Sunohara M, Jo T, Matsui H, Fushimi K, Takami K, Nagase T.
Factors affecting mortality following emergency admission for chronic obstructive pulmonary disease.
BMC Pulm Med. 2014; 14: 151.
PMID: 25253449

Okazaki H, Ishikawa O, Iijima T, Kohira T, Teranishi M, Kawasaki S, Saito A, Mikami Y, Sugiura A, Hashimoto S, Shimada E, Uchikawa M, Matsuhashi M, Tsuno NH, Tanaka M, Kiyokawa N, Fujimoto J, Nagase T, Tadokoro K, Takahashi K.
Novel swine model of transfusion-related acute lung injury.
Transfusion. 2014; 54: 3097-3107.
PMID: 24965098

Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y.
Lymphotoxin beta receptor signaling induces il-8 production in human bronchial epithelial cells.
PLoS One. 2014;9:e114791.
PMID: 25501580

Yamauchi Y, Hasegawa W, Yasunaga H, Sunohara M, Jo T, Takami K, Matsui H, Fushimi K, Nagase T.
Paradoxical association between body mass index and in-hospital mortality in elderly patients with chronic obstructive pulmonary disease in japan.
Int J Chron Obstruct Pulmon Dis. 2014;9:1337-1346.
PMID: 25525351

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